While some sources claim that manganese lowers iron levels, this is mostly a theoretical consideration that would only happen under unusual circumstances. In actual clinical settings, Dr. Ronald Roth had not seen a single case of a patient's iron levels decline as a result of taking manganese, even when doses as high as 150 mg per day were supplemented on an ongoing basis. In fact, most minor iron-deficiency situations can be dealt with by using manganese alone - without any iron - which reduces any potential adverse effects that can be part of routine iron supplementation... Full Text